Do you know of any long-term weight loss possible with anti-obesity drugs? A new study reveals

June 26, 2022 4:14 p.m. STI

Washington [US]Jun 26 (ANI): According to a recent study, a group of researchers found that overweight and obese people maintained an average weight loss of 10.6% for more than 3-5 years with the support of a weight loss program. lifestyle change and fight against obesity. medications.
Weight loss of more than 10% offers significant health benefits, according to researchers presenting their findings Sunday, June 12 at ENDO 2022, the Endocrine Society’s annual meeting in Atlanta, Georgia.
“Data on the effectiveness of anti-obesity drugs for long-term maintenance of weight loss in the real world has been limited to 1 to 2 years,” said lead researcher Michael A. Weintraub, MD, of Weill Cornell Medicine in New York, NY. “Our study is unique because we analyzed maintenance of weight loss over 3 to 5 years in over 400 overweight and obese adults taking weight-loss medication.”

The study looked at data from 428 patients at an academic weight management center. All patients received counseling focused on a low glycemic diet and exercise by the obesity medicine specialist during their office visits. Patients also received additional counseling with a registered dietitian.
Medical therapy included FDA-approved, off-label weight-loss drugs. The most commonly used drugs were metformin, phentermine, and topiramate. At last visit, patients were taking an average of two weight management medications.
Patients were followed for a median of 4.7 years. They lost and maintained an average weight loss of 10.6%, which was maintained with medical treatment and lifestyle interventions for 3-5 years.
“A 10% weight loss is clinically significant as it is associated with improvements in cardiovascular risk factors such as diabetes, hypertension, high cholesterol and obstructive sleep apnea as well as improvements in mobility. and overall quality of life,” he said.
Obesity rates are approaching 40% in the United States, Weintraub noted. “Anti-obesity drugs are an underused treatment option for obesity and can prevent obesity-related diseases, including diabetes and cardiovascular disease,” he said. “This research confirms the usefulness of anti-obesity drugs in maintaining long-term weight loss.” (ANI)

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